| Date | Location | Result | |
| 03/02/21 | Highland Heights, KY | Northern Ky. 70, Detroit Mercy 69 | Box score |
| 02/25/21 | Detroit, MI | Detroit Mercy 83, Robert Morris 73 | Box score |
| 02/20/21 | Detroit, MI | Detroit Mercy 80, Robert Morris 61 | Box score |
| 02/19/21 | Detroit, MI | Detroit Mercy 85, Robert Morris 74 | Box score |
| 02/13/21 | Cleveland, OH | Cleveland St. 71, Detroit Mercy 64 | Box score |
| 02/12/21 | Cleveland, OH | Detroit Mercy 89, Cleveland St. 83 | Box score |
| 02/06/21 | Detroit, MI | Detroit Mercy 83, Purdue Fort Wayne 56 | Box score |
| 02/05/21 | Detroit, MI | Detroit Mercy 82, Purdue Fort Wayne 72 | Box score |
| 01/30/21 | Youngstown, OH | Detroit Mercy 77, Youngstown St. 72 | Box score |
| 01/29/21 | Youngstown, OH | Detroit Mercy 78, Youngstown St. 75 | Box score |
| 01/23/21 | Rochester, MI | Detroit Mercy 82, Oakland 72 | Box score |
| 01/22/21 | Rochester, MI | Oakland 86, Detroit Mercy 81 | Box score |
| 01/16/21 | Detroit, MI | Detroit Mercy 68, Green Bay 65 | Box score |
| 01/15/21 | Detroit, MI | Detroit Mercy 86, Green Bay 61 | Box score |
| 12/27/20 | Detroit, MI | Oakland 83, Detroit Mercy 80 | Box score |
| 12/26/20 | Detroit, MI | Oakland 77, Detroit Mercy 75 (OT) | Box score |
| 12/20/20 | Detroit, MI | Wright St. 85, Detroit Mercy 72 | Box score |
| 12/19/20 | Detroit, MI | Wright St. 93, Detroit Mercy 70 | Box score |
| 12/12/20 | Kalamazoo, MI | Detroit Mercy 67, Western Mich. 57 | Box score |
| 12/09/20 | Detroit, MI | Kent St. 80, Detroit Mercy 66 | Box score |
| 12/06/20 | Notre Dame, IN | Notre Dame 78, Detroit Mercy 70 | Box score |
| 12/04/20 | East Lansing, MI | Michigan St. 83, Detroit Mercy 76 | Box score |